LNG-IUS treatment of non-atypical endometrial hyperplasia: Can Pipelle endometrial sampling be an accurate method of follow-up evaluation?
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LNG-IUS treatment of non-atypical endometrial hyperplasia: Can Pipelle endometrial sampling be an accurate method of follow-up evaluation?
(EH) is a common disease affecting women of all ages [1]. It is clinically important because it can cause abnormal uterine bleeding, and can precede, or occur concurrently, with endometrial carcinoma. There are many progestin therapy regimens available for treatment of EH. The main progestational agents are oral pro-gestogens such as norethisterone acetate, megestrol acetate, and medroxyprogest...
متن کاملLNG-IUS treatment of non-atypical endometrial hyperplasia in perimenopausal women: a randomized controlled trial
OBJECTIVE To compare the efficacy of the levonorgestrel-releasing intrauterine system (LNG-IUS) and oral norethisterone acetate (NET) for treatment of non-atypical endometrial hyperplasia in perimenopausal women. METHODS One hundred and twenty perimenopausal women with non-atypical endometrial hyperplasia were selected in this randomized controlled trial. Patients received LNG-IUS (n=59) or N...
متن کاملLNG-IUS versus oral progestogen treatment for endometrial hyperplasia: a long-term comparative cohort study.
STUDY QUESTION What are the regression and hysterectomy rates for women treated with the levonorgestrel-releasing intrauterine system (LNG-IUS) compared with oral progestogens for endometrial hyperplasia (EH)? SUMMARY ANSWER The LNG-IUS achieves higher regression and lower hysterectomy rates than oral progestogens in the treatment of complex and atypical hyperplasia. WHAT IS KNOWN ALREADY T...
متن کاملThe effectiveness of levonorgestrel releasing intrauterine system in the treatment of endometrial hyperplasia in Korean women.
OBJECTIVE Levonorgestrel releasing intrauterine system (LNG-IUS) has been shown to treat patients with non-atypical & atypical endometrial hyperplasia (EH) successfully in many western studies. Our purpose was to examine the effectiveness of LNG-IUS in the treatment of Korean women with EH. METHODS We conducted a prospective observational study of 12 women diagnosed with EH and treated with L...
متن کاملRelapse of endometrial hyperplasia after conservative treatment: a cohort study with long-term follow-up.
STUDY QUESTION What is the risk of relapse for women with endometrial hyperplasia treated with levonorgestrel-releasing intrauterine system (LNG-IUS) or oral progestogens? SUMMARY ANSWER Relapse of complex endometrial hyperplasia after initial regression occurs often and it occurs less often in women treated with LNG-IUS than with oral progestogens. WHAT IS KNOWN ALREADY The LNG-IUS and ora...
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ژورنال
عنوان ژورنال: Journal of Gynecologic Oncology
سال: 2013
ISSN: 2005-0380,2005-0399
DOI: 10.3802/jgo.2013.24.2.103